Our Bone and Immune System Are Connected?

January 16, 2024

Our Bone and Immune System Are Connected?

Hello there! Today, we’re diving into an intriguing area: the interconnection between bone health and immune strength. Understanding this link is crucial for anyone interested in maintaining overall wellness, especially as we age.

The Emerging Field of Osteoimmunology

Osteoimmunology is an evolving field focusing on the fascinating relationship between our skeletal system and immune responses. It appears that our bones and immune system are more connected than we previously thought, sharing molecules and regulatory mechanisms! 

This connection is particularly evident in conditions like osteoporosis, where researchers are exploring how the immune system, particularly its dysfunction in autoimmune diseases, may contribute to bone loss.

Typically, our immune system protects us from harmful pathogens. However, sometimes it malfunctions, producing autoantibodies that mistakenly attack our own healthy cells – this is called autoimmune diseases. These misguided attacks can affect various body parts, including organs, joints, and skin, leading to symptoms that can range from uncomfortable to debilitating.

Autoantibodies and Bone Health

A 2017 review highlighted an important finding: autoantibodies and chronic inflammation can contribute to bone loss. Our immune cells play a vital role in bone remodeling, meaning changes in the immune system can directly impact bone density. This finding is important in understanding and treating conditions like osteoporosis, where bone density is significantly reduced.

Intricate Interactions: Bone and Immune Cells

Recent discoveries have shed light on how bone and immune cells interact. For example, cells related to osteoblasts (bone-forming cells) are crucial in regulating the hematopoietic stem cell niche, which gives rise to blood and immune cells. 

Additionally, osteoclasts (bone-resorbing cells) share a common origin with certain immune cells. These intricate relationships suggest that immune cells and cytokines (immune signaling molecules) may be responsible for changes in bone turnover and mass in various conditions, including postmenopausal osteoporosis and inflammatory diseases like rheumatoid arthritis.

The Bone-Immune System Link

Our bones and immune system don’t just coexist; they actively influence each other… Here’s how:

  1. Shared Origins and Functions: In the bone marrow, there are special cells called hematopoietic stem cells. These cells are like the starting point for creating immune cells. These stem cells work together with the cells that make up your bones. Both your bone system and your immune system use some of the same tools, like cytokines (which help cells talk to each other), receptors (which are like special receiving points on cells), signaling molecules (which send messages between cells), and transcription factors (which help control what a cell does). This means that your bone and immune systems can communicate and influence each other.
  2. The Role of Bones in Immunity: Bones are not just structural elements. They play a crucial role in creating blood cells, including those vital for the immune response. The bone marrow is a primary site for producing white blood cells, which are frontline defenders against infection and disease.
  3. The Impact of the Immune System on Bones: Similarly, the immune system influences bone health. For instance, inflammation, a common immune response, can lead to changes in bone density and structure.

By appreciating the synergy between the bone and immune systems, we can better understand their functions in health and disease. This understanding opens up new avenues for research and potential treatments, emphasizing the need for a holistic approach to health.

The Role of Micronutrients and the Restore Program

Diet plays a pivotal role in maintaining both bone and immune health. As a gut-health nutritionist, I can attest that the right balance of nutrients is vital for strengthening bones and supporting a healthy immune system. This is where my Restore Program comes in. 

Using the Mediator Release Test (MRT), we can identify foods and chemicals that might be affecting your immune response. The MRT tests for reactions to 176 different items, including common foods, additives and naturally occurring chemicals.  Additional testing offered (Spectracell Micronutrient Testing) can provide an unique insight into what functional deficiencies are occuring that can impact your immune, bone and hormonal health (plus much more!)

In the three-month Restore Program for gut health, we work together to revitalize your immune and gut health through a carefully planned elimination diet based on the LEAP protocol. Additionally, I guide you in adopting mindful eating practices, helping you build a healthier relationship with food and your body! 

JOIN THE WAITLIST HERE!

Part 2 Coming Soon

As we navigate the fascinating world of bone health and immune strength, remember that this journey is about more than just understanding; it’s about action! Stay tuned for our Part 2 blog post, where we’ll delve deeper into practical strategies for nurturing these vital systems. 

We’ll explore a range of treatment options and supplements, discuss essential diet changes, and examine the role of key vitamins and minerals. And let’s not forget about exercise – a crucial component of maintaining strong bones and a robust immune system!